once again, wrong sub, but sure.
You start off with 1 million, which is more than enough for leasing a few new aircraft. you need to find a route with relatively high demand, over 2k is good for a start.
Then you need to plan the flight, (keep in mind to utilize the plane as much as possible) and adjust the price.
if you do it right, you can make profit with only one flight.
Feel free to join the game's discord and DM me over there, I can personally help you based on your situation.